CLINICAL STUDIES EVALUATING THE EFFECTIVENESS OF PHASE 2
The leading clinical study carried out to evaluate the effectiveness of Phase
2 was a study conducted in Italy in September 2001. This was a study on 60 volunteers
who were given a capsule before their high starch meals consisting of either
500 mg of Phase 2 or a placebo. After 30 days the Phase 2 group had experienced
an average weight loss of 2.93 kg (6.45 lbs), which was 3.9% of their body weight
and 10.45% of their body fat. The placebo group had an average weight loss of
0.34 kg (0.75 lbs).
A similar study was carried out in the United States in December 2002. In this
study volunteers who were given Phase 2 to take before their high starch meals
lost an average of 3.8 lbs over 8 weeks, this being an over 200% greater loss
than those on a placebo. They also lost an average of 1.5 inches from their
waist measurements, this being a 43% greater loss than those on a placebo.
Another such study was conducted in Norway and published in September 2000.
This study used 40 obese volunteers and over 12 weeks the Phase 2 group achieved
an average weight reduction of 3.5 kg (7.7 lbs), this comparing to a loss of
1.2 kg (2.6 lbs) for the study's placebo group. In addition body composition
measurements showed that more than 85% of the weight loss achieved by the Phase
2 users was fat loss.
A different kind of study measures the amount of starch being absorbed by volunteers
taking Phase 2, rather than the eventual weight they may lose. Such a study
was carried out in the United States in September 2001 with volunteers taking
1500 mg of Phase 2 before eating starch and then having their blood glucose
level monitored. The result was that the glucose level of the volunteers over
a period of 150 minutes after eating was on average 57% less than that of the
placebo group.
This study was repeated in November 2001, with volunteers again taking 1500
mg of Phase 2 before eating starch. This time their glucose level was on average
85% lower than the placebo group, meaning that only 15% of the glucose available
from the food they had eaten had found its way into the body. The glucose also
peaked 15 minutes earlier and cleared from the blood about 30 minutes earlier
than occurred with the placebo group.
A further study of this kind was conducted with volunteers being given Phase
2 when eating a typical full meal, rather than a high starch food alone. The
meal consisted of sirloin beef, mashed potatoes, mushrooms, beans, gravy and
cherry-apple crumb cake. The amount of Phase 2 given to the volunteers in this
study was 750 mg and this was mixed into the mashed potatoes. The result obtained
from taking blood glucose levels was that starch absorption to the body had
been reduced by an average of 28% when compared to the placebo group.
In addition to the above studies using human subjects, a study
using rats has been conducted, published in March 2001. This study
tested the digestive system of the rats for activity of alpha amylase,
the enzyme that breaks down starches, and concluded that administering
Phase 2 to the rats decreased amylase activity by 50 - 75%.
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