Stay Clear Headed With RU-21
As Low As £4.28 per Pack
RU21 is an all-natural supplement that has been clinically
proven to regulate alcohol metabolism in order to prevent alcohol-related
damage to the vital organs of the body.
RU21 was developed by the scientists at the Russian Academy
of Sciences in the course of a 25 year-long research project studying
alcohol metabolism.
LOS ANGELES, April 26 /PRNewswire
A joint study conducted by Russia's top three scientific research
institutes has concluded that the supplement pill RU-21 could have
a distinct effect on alcohol metabolism, which would help reduce
alcohol-related harm to the human body. These findings will be published
in the British scientific journal Addiction Biology. RU-21 is an
all-natural formula currently marketed in the United States as a
dietary supplement.
The test results showed that RU-21 reduces the toxicity of ethyl
alcohol by inhibiting the production rate of acetic aldehyde, the
main poison of alcohol. "Acetic aldehyde boosts the chances
of developing about 60 diseases, including alcoholism, several cancers,
liver cirrhosis and neuropsychological disorders, and also contributes
to hangover effects, such as headache, nausea, etc" says Vladimir
Nuzhny, M.D., Chief of Laboratory of Toxicology at the National
Research Center on Addiction of the Russian Ministry of Public Health.
The study was carried out in accordance with the NIAAA (National Institute
of Alcohol Abuse and Alcoholism) guidelines. Participating institutions included
National Research Center on Addiction of the Russian Ministry of Public Health,
Moscow University of Friendship and Russian Scientific Research Institute of
Health.
How it Works
When alcohol is consumed, it enters cells and is broken down into
acetaldehyde. Acetaldehyde is an extremely toxic compound believed
to be responsible for both, most alcohol-related diseases and the
addictive process itself.
The reaction is as follows: CH3CH2OH+NAD+® CH3CHO+NADN+H+ (1)
Then an enzyme called aldehyde dehydrogenise 2 (ALDH2) converts
the acetaldehyde into acetic acid, which is non-toxic and can be
readily used by the body to provide energy, eventually breaking
down into water and carbon dioxide. However, the body is only able
to metabolize a certain amount of acetaldehyde within a certain
period of time regardless of how much alcohol is being consumed.
Consequently, alcohol consumption often results in excess acetaldehyde
entering blood stream and causing severe damage to the vital organs
and functions of the body.
RU-21 balances alcohol metabolism by slowing down the process
of ethanol oxidation into acetaldehyde, so less acetaldehyde occurs
in the first place, and then speeding up the process of acetaldehyde
decomposition into acetic acid and then water and carbon dioxide.
The first task is the slowing down ethanol oxidation into acetaldehyde
was accomplished by the inclusion of dextrose (glucose) into the
formula. Dextrose rapidly oxidizes in cytosol of liver cells using
the same cytosol NAD pool used by ethanol to convert into acetaldehyde,
thereby creating a deficit of cytosol NAD needed for the reaction
(1) shown above.
Further, the acceleration of decomposition of acetaldehyde and
acetic acid into CO2 and H2O and the energizing of mitochondria
were accomplished through activation of aerobic oxidation processes
in mitochondria by way of introducing substrates (Succinic Acid,
Fumaric Acid), which activate the second half-cycle of tricarboxylic
acids. Succinate substrate, which is independent of NADN-dehydrogenise
prevents acetaldehyde from causing hypoxia, which often results
form the accumulation of suboxidized metabolites, and from impeding
NADN oxidation in the respiratory chain of cells.
L-Glutamine was added to the formula to speed up the mitochondria-cytosolic
malate-aspartate shuttle, which plays key role in the course of
acetaldehyde intoxication development. It also speeds up succinate
oxidation process (by preventing oxalic and acetic inhibition of
succinate dehydrogenase). In addition, it transforms itself into
a-ketoglutarate during a rapid oxidation in Crebs cycle. And finally,
the proper concentration of L-Glutamine positively influences glutamate
and GAMC synapses in the brain, improving coordination and inhibition
processes affected by alcohol intoxication.
Ascorbic Acid was added to the formula in order to activate anti-oxidant
systems of the central nervous system, liver and hormone-active
tissues (affected by hypoxia and acetaldehyde) and to support adrenal
gland cortex, which produces anti-stress hormones.RU-21 is manufacture
and marketed by Spirit Sciences USA, Inc. a California-based company
engaged in the discovery, development, manufacture and marketing
of breakthrough pharmaceutical and nutritional products.The company
employs over 1,000 people and markets its products in 15 countries
in Europe, North America and countries of CIS.
Clinical Trials
were conducted at the Russian Academy of Sciences, Ministry of Public Health
of RF, and earlier at laboratory of the Soviet Military Academy of Sciences.The
analysis of scientific data obtained from those clinical trials proved that
1,0g to 3,0g of RU-21 (0,5g tablets) introduced before or during alcohol consumption,
significantly reduces the risk of alcohol-related diseases as well as mutagenesis
(damage to DNA cells) and also prevents alcohol-induced hangover.
Questions & Answers
| Q: When should I use RU-21? |
A: It is a good idea to always use RU-21 when consuming
alcohol. Using RU-21 with even minimal amounts of alcohol will help
maintain good health and even appearance, since acetaldehyde is also
known to cause premature Ageing of skin. |
| Q: How should I use RU-21? |
A: For best results RU-21 should be taken prior or
during alcohol consumption. |
| Q: How many tablets should I take? |
A: Normally, one-two tablets before and one-two tablets
during alcohol consumption, depending on body weight, amount of alcohol
consumed and whether or not any food is being consumed. However, taking
up to 6 tablets will not result in any undesired side-effects and
many people choose to do so if they're especially susceptible to hangovers. |
| Q: Will RU-21 prevent intoxication? |
A: No, it will not. |
| Q: What sets RU-21 apart from competition? |
A: There is presently no known direct competition. |
|
Each Pack Contains 20 Tablets or 10 Servings
| No. Packs |
Cost Per Pack |
Total Cost |
Saving |
| 1 |
£5.88 |
£5.88 |
£0.00 |
| 5 |
£5.56 |
£27.78 |
£1.62 |
| 10 |
£5.08 |
£50.78 |
£8.02 |
| 20 |
£4.60 |
£92.00 |
£25.60 |
| 30 |
£4.28 |
£128.43 |
£47.97 |
|
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